Translation of a clinical pharmacologist’s conclusion on drug interaction is required to accurately assess risks of combined medication use, adjust therapy and ensure patient safety during international medical treatment
A clinical pharmacologist’s conclusion on drug interaction is a specialised medical document analysing the effects of simultaneous use of several medicines on a patient’s body. It evaluates pharmacokinetic and pharmacodynamic interactions, potential adverse reactions, enhancement or reduction of therapeutic effects, and provides dosage adjustment recommendations. Translation of this document is required for treatment abroad, participation in international clinical trials or consultations with foreign specialists. A high-quality translation ensures accurate transfer of medical terminology, clinical reasoning and recommendations. Preserving the original structure, measurement units and active substance names is essential to avoid medical errors and misinterpretation of data
| Source | Target |
| Based on the patient’s current therapy, co-administration of Drug A and Drug B may result in a significant increase in plasma concentration due to inhibition of hepatic enzymes. This interaction can enhance the pharmacological effect and raise the risk of adverse reactions. Dose adjustment or alternative therapy should be considered. Continuous monitoring of clinical parameters is recommended throughout the treatment period to ensure patient safety and therapeutic efficacy | С учетом текущей терапии пациента совместное применение препарата А и препарата Б может привести к значительному увеличению концентрации в плазме вследствие ингибирования печеночных ферментов. Такое взаимодействие усиливает фармакологический эффект и повышает риск побочных реакций. Рекомендуется рассмотреть коррекцию дозы или альтернативную терапию. На протяжении всего периода лечения необходимо постоянное клиническое наблюдение для обеспечения безопасности и эффективности терапии |
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